The starting point of the itinerary is the Basilica of Santa Maria delle Carceri. Leaving the city to the south, you reach the first of the Medici municipalities, Poggio a Caiano (15 min. by car from the city centre), whose territory, together with that now included in the Municipality of Carmignano, was one of the favorite estates of Lorenzo the Magnificent, Francesco I and the Grand Duke Ferdinando, lovers of the beautiful country houses, hunting trips and great feasts in the gardens. The second stop on the itinerary is the large park of the Cascine di Tavola. In 1473/74 the Magnificent, the most enlightened member of the family, bought a "casa da signore" (mansion) on a small hill and the vast surrounding land, designing the renovation into a new villa that became a noble residence and the centre of a large estate. It was the genesis of Poggio a Caiano Medicean complex which consists of the Villa and its park, the Scuderie (restored in 2000 and now used as an exhibition and conference space) and the Cascine di Tavola (8 a.m.-4 p.m.
in winter, 8 a.m.-8 p.m. in summer). The third stop on the itinerary is Villa Ambra in Poggio a Caiano. Completed in 1520 according to the plan by Sangallo, it is the prototype of the Renaissance villa; the most prestigious room is the Leo X hall, surrounded by an imposing cycle of frescoes painted by Pontormo, Franciabigio, Alessandro Allori and Andrea del Sarto. The villa was always the summer residence of the Medici and the scene of important events in their dynastic history. Here were celebrated the weddings of Alessandro de 'Medici and Margaret of Austria (1536), of Cosimo I and Eleonora of Toledo (1539), between Francesco I and Bianca Cappello (1579). The death of the latters, perhaps due to poisoning, is still shrouded in mystery and stuff of legend. At the time of Cosimo III (second half of the seventeenth century), the villa was equipped with a theatre on the ground floor to satisfy the whims of Marguerite Louise d'Orléans.